Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5621
Gene Symbol: PRNP
PRNP 		0.600 GermlineCausalMutation disease ORPHANET Identification of three novel mutations (E196K, V203I, E211Q) in the prion protein gene (PRNP) in inherited prion diseases with Creutzfeldt-Jakob disease phenotype. 10790216 2000
Entrez Id: 5621
Gene Symbol: PRNP
PRNP 		0.600 Biomarker disease CTD_human Snord 3A: a molecular marker and modulator of prion disease progression. 23349890 2013
Entrez Id: 5621
Gene Symbol: PRNP
PRNP 		0.600 Biomarker disease CTD_human Copper reduction by copper binding proteins and its relation to neurodegenerative diseases. 12572668 2003
Entrez Id: 7280
Gene Symbol: TUBB2A
TUBB2A 		0.300 Biomarker disease CTD_human Snord 3A: a molecular marker and modulator of prion disease progression. 23349890 2013
Entrez Id: 79644
Gene Symbol: SRD5A3
SRD5A3 		0.300 Biomarker disease CTD_human Snord 3A: a molecular marker and modulator of prion disease progression. 23349890 2013
Entrez Id: 151507
Gene Symbol: MSL3P1
MSL3P1 		0.300 Biomarker disease CTD_human Snord 3A: a molecular marker and modulator of prion disease progression. 23349890 2013
Entrez Id: 3119
Gene Symbol: HLA-DQB1
HLA-DQB1 		0.300 Biomarker disease CTD_human
Entrez Id: 79974
Gene Symbol: CPED1
CPED1 		0.300 Biomarker disease CTD_human Snord 3A: a molecular marker and modulator of prion disease progression. 23349890 2013
Entrez Id: 692157
Gene Symbol: SNORA16B
SNORA16B 		0.300 Biomarker disease CTD_human Snord 3A: a molecular marker and modulator of prion disease progression. 23349890 2013
Entrez Id: 319101
Gene Symbol: KRT73
KRT73 		0.300 Biomarker disease CTD_human Snord 3A: a molecular marker and modulator of prion disease progression. 23349890 2013
Entrez Id: 22926
Gene Symbol: ATF6
ATF6 		0.300 Biomarker disease CTD_human Snord 3A: a molecular marker and modulator of prion disease progression. 23349890 2013
Entrez Id: 216
Gene Symbol: ALDH1A1
ALDH1A1 		0.300 Biomarker disease CTD_human Snord 3A: a molecular marker and modulator of prion disease progression. 23349890 2013
Entrez Id: 3822
Gene Symbol: KLRC2
KLRC2 		0.300 Biomarker disease CTD_human Snord 3A: a molecular marker and modulator of prion disease progression. 23349890 2013
Entrez Id: 8360
Gene Symbol: H4C4
H4C4 		0.300 Biomarker disease CTD_human Snord 3A: a molecular marker and modulator of prion disease progression. 23349890 2013
Entrez Id: 780851
Gene Symbol: SNORD3A
SNORD3A 		0.300 Biomarker disease CTD_human Snord 3A: a molecular marker and modulator of prion disease progression. 23349890 2013
Entrez Id: 5621
Gene Symbol: PRNP
PRNP 		0.600 Biomarker disease BEFREE In this review I covered recent data on the vCJD and BSE epidemic, the mode of BSE spreading to humans and, finally, the data on the PRNP analogue--the doppel gene (PRND). 11693716 2000
Entrez Id: 5621
Gene Symbol: PRNP
PRNP 		0.600 Biomarker disease BEFREE The pathology of vCJD showed relatively uniform morphological and immunocytochemical characteristics, which were distinct from other forms of CJD. 12064259 2002
Entrez Id: 5621
Gene Symbol: PRNP
PRNP 		0.600 Biomarker disease BEFREE Molecular analysis of PrP(Sc) (the scrapie isoform of PrP) from cerebellar tissue demonstrated a novel PrP(Sc) type similar to that seen in vCJD (PrP(Sc) type 4). 18071044 2007
Entrez Id: 5621
Gene Symbol: PRNP
PRNP 		0.600 Biomarker disease BEFREE Strain-specific viral properties of variant Creutzfeldt-Jakob disease (vCJD) are encoded by the agent and not by host prion protein. 19097123 2009
Entrez Id: 5621
Gene Symbol: PRNP
PRNP 		0.600 AlteredExpression disease BEFREE For example, cross-sequence transmission of bovine spongiform encephalopathy (BSE) prions to human generated variant Creutzfeldt-Jakob disease (vCJD) prions which retained the transmissibility to mice expressing bovine PrP. 19659941 2009
Entrez Id: 5621
Gene Symbol: PRNP
PRNP 		0.600 Biomarker disease BEFREE Prion protein heterogeneity in sporadic but not variant Creutzfeldt-Jakob disease: UK cases 1991-2002. 15174020 2004
Entrez Id: 5621
Gene Symbol: PRNP
PRNP 		0.600 Biomarker disease BEFREE The single monkey infected with BASE had a shorter survival, and a different clinical evolution, histopathology, and prion protein (PrPres) pattern than was observed for either classical BSE or vCJD-inoculated animals. 18714385 2008
Entrez Id: 5621
Gene Symbol: PRNP
PRNP 		0.600 Biomarker disease BEFREE Human prion protein (PrP) 219K is converted to PrPSc but shows heterozygous inhibition in variant Creutzfeldt-Jakob disease infection. 19074151 2009
Entrez Id: 5621
Gene Symbol: PRNP
PRNP 		0.600 GeneticVariation disease BEFREE To date, all patients with vCJD are homozygous for methionine at codon 129 of the PrP gene. 16480953 2006
Entrez Id: 5621
Gene Symbol: PRNP
PRNP 		0.600 Biomarker disease BEFREE Western blot analysis of PrP(Sc) in the brain in vCJD tissue shows a uniform isotype, with a glycoform ratio characterized by predominance of the diglycosylated band, distinct from sporadic CJD. 15148991 2004